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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEK3 All Species: 15.15
Human Site: S243 Identified Species: 33.33
UniProt: P51956 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51956 NP_001139571.1 506 57705 S243 Q M F K R N P S H R P S A T T
Chimpanzee Pan troglodytes XP_001160306 495 56653 M237 L Q F L V K Q M F K R N P S H
Rhesus Macaque Macaca mulatta XP_001106955 504 57509 S243 Q M F K R N P S H R P S A T T
Dog Lupus familis XP_543184 1286 146207 R244 Q L F K R N P R D R P S V N S
Cat Felis silvestris
Mouse Mus musculus Q9R0A5 511 57204 S241 Q M L K R N P S H R P S A T T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513217 507 57493 T243 Q M F K R N P T Y R P S A T T
Chicken Gallus gallus XP_001232686 498 56944 K243 Q M F K R N P K N R P S A T T
Frog Xenopus laevis Q7ZZC8 944 104521 D274 V H A C L E Q D P E K R P T A
Zebra Danio Brachydanio rerio Q90XC2 697 76523 S244 N M L N L D P S K R P Q L N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CAU7 606 68016 E244 S M L R K N P E L R P S A A E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48479 858 94329 D276 D C L R V N P D R R P D T A T
Conservation
Percent
Protein Identity: 100 96.8 95.4 22.4 N.A. 72.9 N.A. N.A. 74.5 62.2 21.2 24.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.2 96.8 31.6 N.A. 82.9 N.A. N.A. 86.3 76.4 34.2 40.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 60 N.A. 93.3 N.A. N.A. 86.6 86.6 6.6 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 73.3 N.A. 93.3 N.A. N.A. 100 93.3 6.6 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.9 N.A. 23
Protein Similarity: N.A. N.A. N.A. 47.5 N.A. 37.5
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. 60 N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 0 55 19 10 % A
% Cys: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 0 19 10 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 10 0 10 0 0 0 0 19 % E
% Phe: 0 0 55 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 28 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 55 10 10 0 10 10 10 10 0 0 0 0 % K
% Leu: 10 10 37 10 19 0 0 0 10 0 0 0 10 0 0 % L
% Met: 0 64 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 73 0 0 10 0 0 10 0 19 0 % N
% Pro: 0 0 0 0 0 0 82 0 10 0 82 0 19 0 0 % P
% Gln: 55 10 0 0 0 0 19 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 19 55 0 0 10 10 82 10 10 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 37 0 0 0 64 0 10 10 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 10 55 55 % T
% Val: 10 0 0 0 19 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _